Is Vitamin D3 Same As Vitamin D – Did you know that vitamin D actually comes in two different forms: vitamin D2 and vitamin D3? Essential to your health and well-being, vitamin D provides a number of benefits to keep your body functioning properly. In particular, this fat-soluble vitamin supports strong, healthy bones by working with calcium, one of the main bone minerals. How: Vitamin D is needed for your body to absorb calcium.1 But vitamin D also supports muscle function, muscle strength, balance, and immune health.[2, 3]
Because of the important role vitamin D plays in your body’s healthy growth and function, does it matter “what” vitamin D you get? What is the difference between vitamin D and vitamin D3? And how does vitamin D2 get into the mix? Let’s examine what the research says.
Is Vitamin D3 Same As Vitamin D
First, it helps to know where vitamin D (the sunshine vitamin) comes from. You can get this essential nutrient from three main sources: the sun, food, and supplements. But which form of vitamin D is present in these three sources of vitamin D?
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Is there a difference between vitamin D and vitamin D3? Technically, vitamin D describes vitamin D2 and vitamin D3, which are different in some ways but function similarly in the body. Think of vitamin D as an “umbrella term” for a nutrient that comes in several different forms, similar to the B vitamins, which include thiamin, riboflavin, niacin, folic acid and more.
In foods and supplements, vitamin D comes in two main forms (below), which differ chemically only in structure and are well absorbed in the small intestine .
When you get vitamin D (whether through sun exposure, food, or supplements), the body stores it in fat cells, where it lies dormant until needed. The “hydroxylation process” then begins, where the kidneys and liver convert stored vitamin D into active vitamin D, a form the body can use (known as calcitriol). If your body has low levels of vitamin D, D, it can absorb only 10% to 15% of dietary calcium, but with normal levels of vitamin D, your body can absorb 30% to 40% of calcium [ 7].
If you’re wondering why food was fortified in the first place, it goes back to the 1930s when rickets was common. Rickets, a disease that softens and weakens the bones, is caused by a lack of vitamin D. ‡  Almost all of our nation’s milk supply is now fortified, and each one-cup serving contains about 3 mcg (120 IU) of vitamin D Many plant-based milk alternatives (such as almond and soy milk) are fortified with vitamin D2 and/or vitamin D3, as are cereals and a little orange juice. [2, 6]
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Research shows that vitamin D3 is approximately 87% more potent at increasing blood vitamin D levels and produces two to three times more vitamin D storage in the body compared to vitamin D2. and thus vitamin D3 is the preferred solution for vitamin D deficiency ‡ . 9]
Because of the above problems, you can get limited amounts of vitamin D from sunlight and food. While it’s extremely important to add vitamin D-rich foods to your diet, you should also consider supplements. Nature Made offers a variety of vitamin D3 supplements.
In general, the daily requirement of vitamin D (measured in international units) for healthy people depends on age, with recommended doses below:
However, if you are vitamin D‡ deficient, you will probably need more, at least temporarily, until you get your vitamin D status back up to where it should be.
Vitamin D3 (cholecalciferol)
Vitamin D plays an important role in your well-being by supporting healthy bones, maintaining your immune system and other essential functions. You can get this vital nutrient from three main sources: the sun, food, and supplements. What is the difference between vitamin D and vitamin D3? Technically, vitamin D is related to vitamin D2 (which comes from plants) and vitamin D3 (which the body produces naturally and also comes from animal foods). However, both forms work the same way in the body. Research shows that vitamin D2 is less effective than vitamin D3 in raising vitamin D levels in the blood. If you’re an indoor type and spend less than 15 minutes in the sun a day, or if you’ve been diagnosed with vitamin D deficiency. ‡ then a dietary supplement is a great way to increase your vitamin D intake
Keep checking back to the Nature Made blog for the latest science-based articles to help you take ownership of your health.
This information is for educational purposes only and is not intended as medical advice or a recommendation for any specific product. Contact your healthcare provider for more information.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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As a member of the medical and science communication team, Sandra educates healthcare professionals and consumers about nutrition, supplements and health-related issues. Prior to joining Pharmavite, Sandra worked as a clinical dietitian at the University of Chicago Medicine in both the inpatient and outpatient settings. Sandra received her Bachelor of Science in Nutrition with minors in Spanish and Chemistry from the University of Arizona in Tucson, AZ. She received her Masters in Clinical Nutrition from RUSH University in Chicago, IL. As part of her master’s program, Sandra conducted research on physical activity participation and relationships among urban Hispanic women.
Lisa Beach is a seasoned journalist whose work has appeared in The New York Times, Good Housekeeping, Eating Well, Parents, AARP’s Disrupt Aging, Optimum Wellness and dozens of other magazines. She also writes for various health/wellness based brands. Check out her writer page at www.LisaBeachWrites.com.
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Absorption of vitamin D depends on a number of pathways in the human body. We discussed the importance of vitamin D in a wide range of health conditions, including Covid-19, the immune system and bone structures. These articles explain the changes in detail. https:///wp-content/uploads/2021/08/jcem5387.pdf https:///wp-content/uploads/2021/08/jcemE447.pdf We do not have any financial side of the recommendations on our website.
There are no known contraindications to weight loss surgery to prevent a patient from receiving a post-surgery vaccine for COVID.
A patient who has had a duodenal switch, gastrectomy, gastric bypass RNY, or revision surgery for weight loss should get the COVID vaccine. Vaccination should be avoided for several weeks after surgery. Consult your PCP about other possible contraindications.
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Here is a summary of the vaccines and details of each approved as of the date of publication.
Regardless of whether vitamin D protects against COVID-19, adequate levels are important for bone health. “Preventing vitamin D deficiency is always the goal,” Ross wrote. “If the diet does not include vitamin D-fortified milk or natural products such as fish, supplementing with the recommended amount of food (600-1000 IU per day) is a good guarantee. I consider this a ‘good idea’, but I don’t want to create the impression that the diet cannot be sufficient”.
We are all aware of the many roles vitamin D plays in our bodies. This includes immune function along with all the regulatory roles that vitamin D plays in a variety of physiological reactions. There may be a link between low vitamin D and a COVID-19 infection that increases the risk of death, as seen in research articles.
Previously reported publications suggested a possible correlation between ace inhibitors and an increased risk of pulmonary complications of Covid-19. Some researchers suspect that Covid-19 may enter lung cells through ACE receptors.
The Cosmetic Chemist
The initial entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into cells, mainly type II pneumocytes, after binding to its functional receptor, angiotensin-converting enzyme 2 (ACE2), was demonstrated. After viral complex endocytosis, surface ACE2 is depleted, leading to irreversible accumulation of angiotensin II. Local activation of the renin-angiotensin-aldosterone system may mediate lung injury responses to viral insults. ACE stands for angiotensin converting enzyme and ARB an angiotensin receptor blocker. (N Engl J Med 2020;
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