Fluid Around The Brain And Spinal Cord – Nervous System 2: Central and Peripheral Nervous System I Digital Edition: Nervous System 2: Central and Peripheral Nervous System I
This article, the second in a six-part series on the nervous system, considers the structure and major functions of the brain, beginning with the cerebrum.
Fluid Around The Brain And Spinal Cord
This article, the second in a series on the nervous system, examines the central nervous system, focusing on the structure and major functions of the major parts of the brain. The first of these areas consider the cerebrum, which is the largest part of the brain and includes the left and right hemispheres. It also explains the functions of each of the four lobes: frontal, parietal, occipital, and temporal. This review of the central nervous system will be completed in Part 3.
Cervical Spine Anatomy (neck)
Citation: Bayram-Weston Z et al (2022) Nervous System 2: Central and Peripheral Nervous System I. Nursing Times [online]; 118:4.
Authors: Zubeide Bayram-Weston is a member of the Academy of Higher Education and full professor of Biomedical Sciences; Maria Andrade-Sianz is Honorary Associate Professor of Biomedical Sciences; John Knight is Associate Professor of Biomedical Sciences. They are all in the School of Human and Health Sciences at Swansea University.
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Traumatic Spinal Cord Injury
We use cookies to personalize and enhance your experience on our site. Visit our Privacy Policy and Cookie Policy for more information. You can opt out of certain cookies by adjusting your browser settings. You can find more information on how to do it in the cookie policy. By using our site, you agree to our use of cookies. Normal Pressure Hydrocephalus (NPH) is a condition that occurs when cerebrospinal fluid collects in the skull and puts pressure on the brain. This condition is more likely to occur in people over the age of 65. Treatment for this condition involves surgery to place a shunt to drain excess fluid from inside the skull.
Normal pressure hydrocephalus occurs when a slow buildup of cerebrospinal fluid in the skull puts pressure on the brain. The increased pressure disrupts brain function and causes symptoms.
Normal Pressure Hydrocephalus (NPH) is a brain condition that occurs when fluid builds up in or around the brain, impairing brain function. It can affect various brain-related abilities, including thinking and concentrating, memory, movement, and more. The symptoms of PHN are very similar to those of dementia, but PHN is sometimes reversible.
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PHN is most common in people over the age of 65 and becomes more common with age. The average age of onset of this condition is around 70 years.
The only factor that increases the risk of developing this condition is increasing age. The chance of it happening does not change depending on race, ethnicity, gender, etc. of a person.
NPH is a relatively uncommon condition, but it is widely known. It affects 0.2% of people between 70 and 80 years of age and 5.9% of people over 80 years of age. That means it affects 8.4 million people over the age of 80 worldwide. Experts estimate that PHN is rare in people under the age of 65, but it affects 0.003% of people in that age group.
Cerebrospinal Fluid (csf) Leak: Symptoms & Treatment
NPH is caused by a buildup of cerebrospinal fluid (CSF) in your brain. CSF is a fluid that supplies the brain with nutrients and removes waste. Adults normally have only 5 fluid ounces (150 milliliters) of CSF, less than half the amount of fluid in a standard can of beverage. Your body is constantly creating, circulating, and reabsorbing CSF to keep fluid levels constant.
Although it doesn’t look very runny, it still has a great effect. A small amount of cerebrospinal fluid surrounds the brain and spinal cord, and the brain actually floats in it. The CSF protects the brain and spinal cord from outside forces. If your body can’t properly circulate or reabsorb CSF, it can cause too much of this fluid to build up in your skull.
With NPH, this buildup of fluid usually occurs slowly enough that the pressure inside your skull (intracranial pressure) increases, but remains within normal limits (hence the name, “normal pressure hydrocephalus”). This can cause fluid to build up in part because your brain has fluid-filled spaces called ventricles.
Definition Of Cerebrospinal Fluid Diversion
However, if the CSF continues to build up, the fluid has nowhere to go. When that happens, your brain begins to compress and sag, causing the symptoms of the condition. If the compression of your brain lasts long enough, the pressure can permanently damage or destroy brain tissue.
The symptoms of NPH usually start slowly, develop, and worsen over three to six months. The three main symptoms of NPH are known as Hakim’s triad. Between 50% and 75% of people with PHN show all three symptoms at the same time. Hakim’s triad includes three types of symptoms (more information on each type of symptom directly below):
Gait problems are when you have problems with the movements associated with walking. It is most likely to occur in three types of symptoms. Between 80% and 95% of people with NPH show these symptoms. Some of these symptoms are similar to the movement-related symptoms of Parkinson’s disease, but the main difference is that NPH symptoms usually only affect the legs and feet.
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Urinary incontinence is the loss of bladder control, which causes involuntary urination. Initially, this may cause you to urinate more often or feel an unusually strong or difficult urge to urinate, or both.
People with this symptom may feel embarrassed when they lose bladder control. However, some do not seem to care or feel ashamed. The third type of symptom in Hakim’s triad may be shamelessness or shame due to cognitive difficulties.
A third important symptom of NPH is cognitive difficulties. It is a symptom that appears or is caused by one of the following:
Protection Of The Brain
Primary NPH means that it is not caused by another medical condition. Another word for this is “idiopathic,” a term used by experts for conditions that occur for unknown reasons. Experts suspect that idiopathic NPH may involve one or more age-related problems in the way your body makes, circulates, and reabsorbs CSF. Approximately half of PHN cases are idiopathic.
Under normal circumstances, your body produces 400 to 600 ml of CSF a day. That’s much more than you need, so your body has to constantly reabsorb old CSF to make room for new CSF. If there is a problem with the way CSF is circulated or reabsorbed, this fluid can build up because your body is making more than it needs.
There is evidence that NPH is associated with degenerative brain conditions, such as Alzheimer’s disease, Lewy body dementia, or similar conditions. Researchers continue to investigate exactly how and why PHN occurs, and whether other conditions can cause it. The answers to those questions can ultimately help prevent or better treat the condition.
The Spine’s Self Defense System
Secondary PHN occurs when another medical condition affects the way your body makes, circulates, or reabsorbs CSF. Some examples of conditions that can cause secondary PHN include:
NPH is often difficult to diagnose because the condition shares many symptoms with dementia and similar age-related conditions. It is also common for NPH to occur at the same time as age-related conditions. About 30% of people with NPH have Alzheimer’s disease or a similar degenerative brain disease.
Depending on your symptoms, your healthcare provider may order other tests. This is usually done to rule out other conditions with similar symptoms to PHN. Your provider can tell you more about the tests they recommend and what they think will help.
Cerebrospinal Fluid Is A Clear Fluid In The Brain And Spinal Cord Stock Illustration
In general, PHN is usually a treatable condition. The approach to treatment varies depending on whether the PHN is primary/idiopathic or secondary. Unlike most brain-related conditions, NPH rarely requires medication. This is because PHN does not respond to medicines (although medicines can treat some of the symptoms associated with PHN).
Primary/idiopathic PHN is usually treatable. The most common and effective treatment for idiopathic PHN is surgery to place a device called a shunt. A shunt consists of two tubes (known as catheters), one to let fluid in and one to let fluid out, with a valve between them. As the ventricle fills with excess fluid, the increased pressure forces fluid into the inlet catheter, which opens the valve and allows excess fluid to flow out of the outlet catheter.
Some modern shunt valves are programmable, allowing your provider to adjust the settings without surgery. They also show up on X-rays so your provider can see the valve and make sure the settings are correct. Some modern shunts are MRI-safe, meaning you can still have an MRI even if you have one of these valves.
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The outflow catheter goes through a small hole in your skull (this is opened by your provider during surgery to place the shunt). After the catheter comes out of your skull, it turns down and goes under your skin. A draining catheter allows fluid to drain into the chest or abdomen.
If the tube drains into your abdomen (which is more common), the peritoneum (a membrane)
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